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Cancer: Squamous Cell Carcinoma

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Total 19037 results found since Jan 2013.

Building a gold standard to construct search filters: a case study with biomarkers for oral cancer.
CONCLUSIONS: The gold standard dataset is likely to be high quality and useful for future development and evaluation of filters for OSCC studies of potential prognostic biomarkers. IMPLICATIONS: The methodology we used is generalizable to other domains requiring a reference standard to evaluate the performance of search filters. A gold standard is essential because the labels regarding relevance enable computation of diagnostic metrics, such as sensitivity and specificity. Librarians and informationists with data analysis skills could contribute to developing gold standard datasets and subsequent filters tuned for thei...
Source: Journal of the Medical Library Association : JMLA - January 4, 2015 Category: Databases & Libraries Tags: J Med Libr Assoc Source Type: research

Human blood plasma proteome mapping for search of potential markers of the lung squamous cell carcinoma.
Authors: Shevchenko VE, Kovalev SV, Arnotskaya NE, Zborovskaya IB, Akhmedov BB, Polotskii BE, Kostin AU, Moukeria AF, Zaridze DG, Davidov MI Abstract Blood plasma proteomes obtained from 77 lung squamous cell carcinoma (LSCC) patients (Stages I-III) and 67 healthy controls (all males) were analyzed by using the label-free liquid chromatography tandem mass spectrometry (LC-MS/MS) method for the search of potential cancer biomarkers. All plasma samples were depleted of 14 highly-abundant plasma proteins by immune-affinity column chromatography before LC-MS/MS. We identified and quantified 809 differential proteins wi...
Source: European Journal of Mass Spectrometry - December 1, 2014 Category: Chemistry Tags: Eur J Mass Spectrom (Chichester, Eng) Source Type: research

Performance of 18 F-FDG-PET/CT as a next step in the search of occult primary tumors for patients with head and neck squamous cell carcinoma of unknown primary: a systematic review and meta-analysis
Conclusions18F-FDG PET/CT is useful as a next step in the search of occult primary tumors in HNSCC-UP patients defined by endoscopy with or without CT/MRI. However, in light of the high false-positive proportion, confirmatory histological investigations should be viewed as necessary practice upon positive PET/CT findings.
Source: Clinical and Translational Imaging - May 15, 2021 Category: Radiology Source Type: research

Performance of 18F-FDG-PET/CT as a next step in the search of occult primary tumors for patients with head and neck squamous cell carcinoma of unknown primary: a systematic review and meta-analysis
Conclusions18F-FDG PET/CT is useful as a next step in the search of occult primary tumors in HNSCC-UP patients defined by endoscopy with or without CT/MRI. However, in light of the high false-positive proportion, confirmatory histological investigations should be viewed as necessary practice upon positive PET/CT findings.
Source: Clinical and Translational Imaging - August 1, 2021 Category: Radiology Source Type: research

Reviewing the genetic alterations in high ‐risk cutaneous squamous cell carcinoma: A search for prognostic markers and therapeutic targets
Abstract Cutaneous squamous cell carcinoma (SCC) is second only in incidence to basal cell carcinoma (BCC), effecting up to 500 000 people in the United States annually. Metastasis to regional lymph nodes occurs in approximately 5% of cases and imparts significant morbidity. Standard treatment in this group involves a combination of surgery and adjuvant radiation. Currently, there are no clinically useful biomarkers of metastatic potential in primary cutaneous SCC and histological predictors can be unreliable. The high level of mutational burden in normal UV‐exposed skin has hampered the search for novel drivers of inva...
Source: Head and Neck - April 3, 2017 Category: ENT & OMF Authors: Bruce G. Ashford, Jonathan Clark, Ruta Gupta, N. Gopalakrishna Iyer, Bing Yu, Marie Ranson Tags: BASIC SCIENCE REVIEW Source Type: research

Is Lipidomic the Answer to the Search of a Biomarker for Organ Preservation Protocol in Head and Neck Squamous Cell Carcinoma?
In conclusion, we demonstrated that a group of lipids is differentially abundant in saliva from HNSCC patients submitted to an organ preservation protocol, being able to differentiate responders from non-responders. These results suggest the potential use of lipid biomarkers to identify patients who may benefit from this treatment. Also, we showed that saliva testing might be routinely used in clinical practice, for being a non-invasive alternative to blood testing, besides inexpensive and easy to obtain. PMID: 29130149 [PubMed - as supplied by publisher]
Source: Pathology Oncology Research - November 13, 2017 Category: Pathology Authors: Laus AC, da Silva IDCG, Cordeiro FB, Lo Turco EG, de Souza Viana L, Carvalho AL Tags: Pathol Oncol Res Source Type: research

Evaluation of metastatic neck nodes search for primary and subsequent management
CONCLUSIONS: Metastatic neck disease is a major problem in patients with head-and-neck cancer. The therapeutic goal includes not only known disease but also the elimination of possible subclinical disease. The judicious use of moderate doses of irradiation and modified surgical procedures should be used in specific clinical situations to significantly decrease neck recurrences while eliminating morbidity.PMID:35381772 | DOI:10.4103/jcrt.JCRT_1083_20
Source: Cell Research - April 6, 2022 Category: Cytology Authors: Ashutosh Gupta Inderpal Singh Meenu Gupta Isha Puri Source Type: research

Active search screening for oral potentially malignant disorders and oral cancer and in the city of piracicaba
Oral cancer is a world public health problem. Squamous cell carcinoma (SCC) represents approximately 90% of all oral malignancies and is frequently preceded by oral potentially malignant disorders (OPMDs). Screening programs aimed at early detection of oral lesions have been conducted. Therefore, the objective of this research was to carry out an active search screening program in the city of Piracicaba.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - August 17, 2022 Category: ENT & OMF Authors: Matheus Ferreira Linares, Silvia Maria Paparotto Lopes, Adriana Eliza Brasil Moreira, Pablo Agustin Vargas, Alan Roger Dos Santos Silva, M árcio Ajudarte Lopes Source Type: research

The Patient Perspective: Evaluating the Accessibility of Transoral Robotic Surgery Online Resources
CONCLUSIONS: In comparison to other common otolaryngology procedures, TORS websites are the least patient friendly. As TORS becomes a more widely used procedure, it is critical that TORS websites become higher quality resources that patients can reliably reference.PMID:33843290 | DOI:10.1177/00034894211007248
Source: The Annals of Otology, Rhinology, and Laryngology - April 12, 2021 Category: ENT & OMF Authors: Monica H Xing Raymond L Chai Source Type: research

Association Between Cancer Incidence and Mortality in Web-Based Data in China: Infodemiology Study
Conclusions: Search behaviors indeed reflect public awareness of cancer from a different angle. Research on internet search behaviors could present an innovative and timely way to monitor and estimate cancer incidence and mortality rates, especially for cancers not included in national registries.
Source: Journal of Medical Internet Research - January 29, 2019 Category: General Medicine Authors: Chenjie Xu Yi Wang Hongxi Yang Jie Hou Li Sun Xinyu Zhang Xinxi Cao Yabing Hou Lan Wang Qiliang Cai Yaogang Wang Source Type: research